Light Sources

Mightex

Mightex Optogenetics Systems

Mightex Systems, with operations based in Toronto, Canada, and in the Silicon Valley, California, is a leading supplier of photonic products and services for a broad spectrum of applications including industrial imaging, bio-photonic solutions, LED illumination, machine vision, life & health sciences, and industrial test & measurement etc.

Website: http://www.mightex.com

Mightex Optogenetics Systems

BioLED Sources & Controllers


BioLED Sources
Microscopy LEDs

Mightex has developed RMS-series high-power LED turn-key systems to produce homogeneous, high-intensity, wide-field illumination under a microscope. In addition to the superb optical performances, the LED systems also feature fast switching & quick time response, as well as advanced software and/or synchronization capabilities so that customers can easily integrate the LED source into a larger system. The RMS-series high-power LED systems are compatible with most microscopes including Leica, Nikon, Olympus and Zeiss, and you may simply specify the appropriate microscope adapter when placing your order.

  • Single-Wavelength
  • Multi-Wavelength
  • Wavelength Switchable


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Fiber-Coupled LEDs
Fiber Coupled LED

Mightex BLS-series fiber-coupled LED’s employ the latest high-power LED technologies and a proprietary coupling optics to achieve maximum optical output power. In conjunction with BioLED light source control modules, these LED sources can be used for a wide range of applications including optogenetics and other bio-photonics applications.

  • Single-Wavelength
  • Multi-Wavelength
  • Optogenetic Starter Kits


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Lightguide-Coupled LEDs
Lightguide-Coupled LEDs

Mightex BLS-series BioLED light sources are modularized fully-customizable turn-key solutions for optogenetics, fluorescence excitation, and other biophotonics applications. Precisely-timed and high-intensity light pulses are required in optogenetics experiments to activate channelrhodopsins (ChR2, ChR1 etc.) and halorhodopsins (NpHR) in order to excite and inhibit neurons. To meet these requirements, Mightex has developed a proprietary “IntelliPulsing” technology to allow BLS-series sources to output significantly higher power in pulse mode than what the LEDs are rated for in CW mode.

  • Single-Wavelength


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Spotlight LEDs
Lightguide-Coupled LEDs

Mightex BLS-series BioLED light sources are modularized fully-customizable turn-key solutions for optogenetics, fluorescence excitation, and other biophotonics applications. Precisely-timed and high-intensity light pulses are required in optogenetics experiments to activate channelrhodopsins (ChR2, ChR1 etc.) and halorhodopsins (NpHR) in order to excite and inhibit neurons. To meet these requirements, Mightex has developed a proprietary “IntelliPulsing” technology to allow BLS-series sources to output significantly higher power in pulse mode than what the LEDs are rated for in CW mode.


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BioLED Controllers
Manual/Analog LED Controllers
Manual/Analog LED Controllers

Mightex BLS-1000-2, BLS-3000-2, BLS-13000-1, and BLS-18000-1 LED controllers are designed for driving Mightex LED sources. The controllers have two operation modes: Manual Mode: the output curent can be controlled by manually turning the knobs; or trigger Mode: the output current can be controlled via an external analog input signal between 0 ~ 5V.


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Software/TTL LED Controllers
Software/TTL LED Controllers

Mightex BLS-SA/PL series BioLED control modules are modularized fully-customizable turn-key solutions for optogenetics, fluorescence excitation, and other biophotonics applications. Precisely-timed and high-intensity light pulses are required in optogenetics experiments to activate channel-rhodopsins (ChR2, ChR1 etc.) and halorhodopsins (NpHR) in order to excite and inhibit neurons. To meet these requirements, Mightex has developed a proprietary “IntelliPulsing” technology to allow BLS-series sources to output significantly higher power in pulse mode than what the LEDs are rated for in CW mode.


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I/O Control Module
I/O Control Module

Mightex BioLED Analog and Digital I/O Control Module is a system-level control solution to be used in conjunction with the BioLED Manual/Analog Controlled LED Controllers and with the Polygon400 Pattern Illuminator. It greatly extends the flexibility and ease of system-level set-up when working with Mightex’s Polygon400 systems.


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Mightex Optogenetics Systems

Polygon400: Targeted Photostimulation System


Patterned Illumination Systems

The Polygon400 is the market-leading patterned illuminator that provides precise spatio-temporal control of light with single-cell or sub-cellular resolution, making it the perfect illumination tool for life science research. Compatible with any upright or inverted microscope, Polygon400 enables researchers to send light to anywhere on their specimen, and in any shape, size and complexity. In addition, multiple regions of interest can be illuminated simultaneously, and different wavelengths of light can be used with the Polygon400 for different bioscience applications. Furthermore, the Polygon400 can be seamlessly integrated via TTL into a larger system with other equipment such as electrophysiology equipment or cameras.

Key Features
  • Illuminate any shape or size
  • Multi-Wavelength Illumination
  • Simultaneous Multi-Region illumination
  • Fast Pattern Switching
  • Fits on any microscope
  • External Equipment Synchronization
  • Third-Party Camera Compatible
Target Applications
  • Neuroscience: Single-Cell Resolution Optogenetics
  • Cell Biology: Sub-Cellular Resolution Optogenetics
  • Freely-Behaving Optogenetics
  • Cortex-Wide Optogenetics
  • Photobleaching
  • Uncaging

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