Dip Pen Nanolithography (DPN®) is an established method of nanofabrication based on atomic force microscopy (AFM). It enables the precise control of materials transferred from a tip to a substrate. Custom-designed nanoscale features are easily fabricated using “inks” comprised of a wide range of materials from nanoparticles and thiols to DNA and proteins. The development of new ink formulations, optimized deposition protocols and ink delivery devices has advanced DPN from a fundamental research tool to an easy-to-use nanofabrication system.
|Richard D. Piner, Jin Zhu, Feng Xu, Seunghun Hong and Chad A. Mirkin
|Abstract: A direct-write “dip-pen” nanolithography (DPN) has been developed to deliver collections of molecules in a positive printing mode. An atomic force microscope (AFM) tip is used to write alkanethiols with 30-nanometer linewidth resolution on a gold thin film in a manner analogous to that of a dip pen. Molecules are delivered from the AFM tip to a solid substrate of interest via capillary transport, making DPN a potentially useful tool for creating and functionalizing nanoscale devices.|
|The DPN5000 from Nanoink
||The NLP2000 from Nanoink
The DPN 5000 is the latest member of the NSCRIPTOR™ family of nanofabrication products. It combines versatile nanopatterning capabilities with high-performance AFM imaging. Together with a complete suite of micro-electro-mechanical systems (MEMs) based ink delivery devices, users may begin creating their own nanostructures hours after installation.
A new, ultra-low noise scanner with closed loop flexure technology allows for accurate and repeatable nanoscale
patterning in x, y and z. A low coherence laser with small spot size ensures high quality lateral force (LFM) imaging for the improved detection of chemically patterned substrates.
Operating on an industry standard Linux® controller and with input from over one hundred users worldwide, NanoInk has developed new InkCAD™ 4.0 software for improved control of tip-based patterning. Customer partnerships have led to the development of innovative probe technologies tailored to user applications. NanoInk’s MEMs facility manufactures single probes, 1D or 2D passive and active probe arrays, ink delivery systems and substrates designed to maximize the capabilities of the NSCRIPTOR product family.Download Datasheet
The NLP 2000 is an easy to use and affordable desktop nanofabrication system. Virtually anyone can use it. Patterns of nano to micron-sized features can be created with a wide variety of materials from metal nanoparticles to biomolecules. Researchers are able to rapidly design and create custom engineered and functionalized surfaces, using the proven technique of Dip Pen Nanolithography® (DPN®) to transfer minute amounts of materials (easily less than nanoliters) over a large, environmentally controlled work area.Download Datasheet
|Specification||DPN 5000||NLP 2000|
|Patterning Area||90 x 90 um||40 x 40 mm|
|X, Y Position Accuracy||0.25 nm||25 nm|
|Z range||8 um||10 mm|
|Characterization||AFM||Optical (< 1 µm)|
|Maximum sample size||2” diameter||6” diameter|
|Low res xy stage||Low res xy stage||NA|
|DPN 5000||NLP 2000|
|What can it print?||“molecular ink”
- thiols (ODT, MHA)
- nucleic acid
|Multiplexing||- more difficult due to diffusive nature of molecular inks||- easy via inkwells|
|Compatible substrates||Silicon, silicon dioxide, silanized surfaces, amine functionalized slides, metals, PDMS, hydrogels, polystyrene||Silicon, silicon dioxide, silanized surfaces, amine functionalized slides, metals, PDMS, hydrogels, polystyrene|
|Comments||“Manual” re-inking capabilities means: The cantilevers are loaded once, then almost infinite printing is possible. But the inkwells used for the NLP 2000 can be used for the DPN 5000, too.
The built-in AFM has got a 90 x 90 x 10 um scan range
DPN 5000 is replacing the NScriptor
|“Automated” re-inking means: Cantilevers can be reloaded via the inkwells.|
NSCRIPTOR™ DPN System