Neuroanatomical Analysis

MBF Bioscience Microbright field Spot

MBF Bioscience design quantitative imaging software for stereology, neuron reconstruction and image analysis, integrated with the world’s leading microscope systems to empower your research. Their development team and staff scientists are actively engaged with leading bioscience researchers, constantly working to refine their products.

Website: http://www.mbfbioscience.com

Neurolucida

MBF Bioscience Microbright field

Neurolucida


An advanced system for neuron tracing and reconstruction, neuron analysis, and 3D brain mapping


Analyze the structure of neurons by tracing them in 3D with Neurolucida. Trace neurons at a microscope from a physical slide, or at a computer with image stacks. Obtain a wide variety of quantitative data about dendrites, axons, nodes, synapses, and spines.

Neurolucida is advanced scientific software for brain mapping, neuron reconstruction, anatomical mapping, and morphometry. Since its debut more than 20 years ago, Neurolucida has continued to evolve and has become the worldwide gold-standard for neuron reconstruction and 3D mapping. Researchers have reconstructed tens of thousands of neurons using our technology.

The user-friendly interface gives you rapid results, allowing you to acquire data and capture the full 3D extent of neurons and brain regions. You can reconstruct neurons or create 3D serial reconstructions directly from slides or acquired images, and Neurolucida offers full microscope control for brightfield, fluorescent, and confocal microscopes.

Neurolucida is available in two separate versions: Standard, which controls research microscope hardware and Workstation, for offline analysis away from the microscope. The software provides automatic analysis of hundreds of quantitative parameters, with results presented in graphical and spreadsheet format, all exportable to Microsoft Excel ®.

More information at MBF Bioscience's website: click here


Extension Modules
AutoNeuron

AutoNeuron traces neurons from image stacks or whole slides in minutes, significantly reducing time and effort. AutoNeuron works with brightfield, widefield fluorescence, and confocal images.

AutoNeuron

AutoSpine

AutoSpine is a ground-breaking tool for automatic detection and quantification of dendritic spines. Using high-quality dendritic tracings from AutoNeuron or Neurolucida, AutoSpine identifies and counts the spines along the traced dendrites.

AutoSpine

AutoSynapse

AutoSynapse, an extension module for Neurolucida, automatically detects and analyzes pre-synaptic markers such as synaptophysin and post-synaptic markers such as PSD95, then uses nearby dendrites traced with AutoNeuron or Neurolucida to analyze which of those synaptic markers are associated with particular dendrites.

AutoSynapse

Other Modules

AutoSynapse, an extension module for Neurolucida, automatically detects and analyzes pre-synaptic markers such as synaptophysin and post-synaptic markers such as PSD95, then uses nearby dendrites traced with AutoNeuron or Neurolucida to analyze which of those synaptic markers are associated with particular dendrites.

  • Virtual Tissue 3D for creating 3D whole slide images
  • Virtual Tissue 2D for creating 2D whole slide images
  • Image Montaging for automated 3D montaging/stitching of image stacks
  • Image Stack and 3D Visualization for acquiring and viewing 3D image stacks
  • Deconvolution for the deconvolution of brightfield, widefield fluorescence, and confocal images
  • Structured Illumination for integration with structured illumination microscopy hardware
  • Zen control for integration with Zeiss LSM confocal microscopes
  • Open confocal control for integration with confocal microscopes
  • Fluoview control for integration with Olympus Fluoview 300 & 500.
 

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