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Fluorescence Microscopy LED light source

Aug 28, 2026
Category: General
Fluorescence Microscopy LED light source
Fluorescence Microscopy LED light source

The pE-300lite from CoolLED is a high-intensity white-light LED illumination system designed for fluorescence microscopy. Comprising a light source, control pod and power supply, it provides intense, broad-spectrum illumination and is an ideal solution for research laboratories.

The illuminator delivers broad-spectrum illumination, across the excitation bands of commonly used fluorophores including DAPI, CFP, Aqua, FITC, TRITC, TxRed, Cy5 and many more. The system is operated via a remote manual control pod, providing instant on/off functionality and precise irradiance control from 0–100%.

Two pE-300lite configuration options are available: direct fit or liquid-light guide. The direct fit configuration delivers higher irradiance while reducing both purchase and running costs.

For confocal microscopes, the liquid-light guide configuration provides an ideal replacement to traditional metal halide illumination. It enables samples to be viewed prior to scanning while helping to minimise photobleaching and phototoxicity. For laboratories looking to improve safety and sustainability, LED microscope illumination offers significant advantages over traditional mercury and metal halide lamps, which contain hazardous materials. At full power across all three channels, the pE-300lite consumes just 60 W—considerably less than some other LED illumination technologies, which can consume between 120 and 350 W.

With a long operational lifetime and a comprehensive range of microscope adaptors, the pE-300lite can be fitted to most modern and older microscope systems. Its LED technology eliminates the need for bulb replacement or regular optical alignment, allowing the system to provide reliable illumination for many years with minimal maintenance.

The result is a safe, convenient and cost-effective illumination solution with no additional bulb replacement or alignment costs. The pE-300lite is supplied with a 36-month warranty.

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